A study of 4 patients with steroid-resistant nephrotic syndrome who developed urinary decoy cells and BK viruria positivity

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Children with Steroid-resistant Nephrotic Syndrome: a Single-Center Study

Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...

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children with steroid-resistant nephrotic syndrome: a single-center study

background and aim: steroid-resistant nephrotic syndrome (srns) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. these patients are at risk of developing end-stage renal disease. the aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with srns.materials and met...

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Steroid Resistant Nephrotic Syndrome

Minimal Change disease (MCD) is the most common cause of Nephrotic Syndrome (NS) in children accounting for 70 to 90% of cases under the age of 10 years and 50% in older children.In adults MCD is found in 10 to 15% of cases with primary nephrotic syndrome. Most patients with MCD remit with steroids.1 Remission is defined as absence of proteinuria (urine albumin nil or trace on 3 conservative da...

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Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome.

BACKGROUND AND OBJECTIVES Steroid-resistant nephrotic syndrome overwhelmingly progresses to ESRD. More than 30 monogenic genes have been identified to cause steroid-resistant nephrotic syndrome. We previously detected causative mutations using targeted panel sequencing in 30% of patients with steroid-resistant nephrotic syndrome. Panel sequencing has a number of limitations when compared with w...

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Chapter 4: Steroid-resistant nephrotic syndrome in children

INTRODUCTION This chapter makes treatment recommendations for children aged 1 to 18 years with nephrotic syndrome, who do not achieve a complete remission with corticosteroid therapy, i.e., SRNS. This chapter does not apply to children with SRNS under 1 year of age, nor to SRNS due to histologic patterns of glomerular injury other than MCD, MPGN, or FSGS. The cost implications for global applic...

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ژورنال

عنوان ژورنال: Nihon Shoni Jinzobyo Gakkai Zasshi

سال: 2011

ISSN: 1881-3933,0915-2245

DOI: 10.3165/jjpn.24.1